A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Midway via his job, Cees Dekker reinvented himself. Right after decades of hardcore physics, he shifted his target to ‘nanobiology’ within the switch of the millennium. A expression he coined himself, like a make any difference of simple fact.
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
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2007, first true-time detection of strand Trade in homologous recombination by RecA; discovery of a minimal persistence duration of finishes of microtubules; and resolved the mechanism of biosensing with carbon nanotubes
We build level-of-care diagnostics exam of neglected tropical disorders in source-limited configurations, determined by Crspr/Cas9 detecting of pathogen’s DNA in entire body fluids.
During the a long time subsequent these discoveries, my study interests shifted to biophysics and nanobiology, And that i grew to become significantly less associated with the event of nanotube electronics. The main target of many researchers in the sphere also shifted to graphene (wherever, funnily ample, the initial graphene ribbons had been described as ‘nanotubes which have been Slice open along their duration’) right after the discovery of the two-dimensional substance in 2004.
We form germs into forms that deviate from their natural phenotype. Specifically, I'll exhibit our capacity to form Reside E. coli germs into novel styles for example rectangles, squares, triangles and circles.
2000, discovery that nanotubes can carry incredible big latest densities; resolved the controversial concern of Digital transportation via DNA molecules by measurements ceesdekker of insulating habits at The one molecule level; and demonstration of an AFM strategy for one-molecule manipulation of nanotubes
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Presently, we also understood that it ought to be doable to implement one semiconducting carbon nanotube to generate a transistor — and we set out to make it. We stretched person semiconducting nanotubes throughout metallic electrodes and made use of the fundamental silicon substrate being a gate electrode, setting up the basic a few-terminal structure of the area-effect transistor (Fig.
Example (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in grey, the rim of your pore is highlighted in purple, as well as a 3D rendering in the motion with the DNA rod is shown.
2001, discovery of solitary-electron transistors at area temperature based upon nanotubes; realization of initially logic circuits with carbon nanotube equipment; and discovery of your molecular composition of DNA maintenance enzymes with AFM
Enable’s first appear back again at this time when you decided to shift your focus from superconductivity and nanotubes to biology at the end of the 1990s.
Supercoiling-dependent DNA binding: quantitative modeling and applications to bulk and one-molecule experiments